Long-Term Followup of a Multicenter Cohort of 101 Patients With Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)

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Churg–Strauss syndrome (eosinophilic granulomatosis with polyangiitis): A case report

Churg–Strauss syndrome (CSS) is a rare systemic vasculitis of the small and medium sized blood vessels. The triad of asthma, sinusitis and hypereosinophilia is characteristic of CSS. However, it can affect any organ system with predominance for the skin, respiratory, neurological, gastrointestinal and cardiovascular systems. The natural history of the condition has been described in three phase...

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Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) Presenting as Diffuse

Marc-Etienne Parent, MD (Corresponding Author) 5 Résident, Département de Médecine Interne, Université de Sherbrooke 6 3001 12 Avenue, Fleurimont, QC, Canada J1H 5N4 7 Tel : 1-506-229-2155 8 Email : [email protected] 9 10 Benjamin Ellezam, MD, PhD, FRCPC 11 Professeur adjoint de clinique, Pathologie et biologie cellulaire, Université de Montréal 12 Directeur, Programme de résid...

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Eosinophilic myocarditis as a first presentation of eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

We present the case of a 28-year-old man who presented with chest pain and elevated cardiac biomarkers, with no evidence of acute ischaemia. He had a pronounced eosinophilia, abnormal echocardiographic, cardiac MRI and CT findings. He underwent transbronchial biopsy of carinal lymph nodes and of lung parenchyma. Endomyocardial biopsy yielded an eosinophilic infiltrate. He was treated with high ...

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Serum Biomarkers in Patients with Relapsing Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss)

INTRODUCTION Previous studies suggest a role for eotaxin-3, TARC/CCL17 and IgG4 in newly-diagnosed patients with eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss) with highly active disease. The role of these biomarkers in relapsing disease is unclear. METHODS Serum levels of TARC/CCL17, eotaxin-3, IgG4, and IgG4/IgG ratio were determined in serum samples from a longitudinal...

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Solid malignancies among etanercept-treated patients with granulomatosis with polyangiitis (Wegener's): long-term followup of a multicenter longitudinal cohort.

OBJECTIVE An association between therapeutic inhibition of tumor necrosis factor (TNF) and solid malignancies was observed during the Wegener's Granulomatosis Etanercept Trial (WGET), which included 180 patients with granulomatosis with polyangiitis (Wegener's) (GPA). The present study was conducted to determine the malignancy risk beyond the time of exposure to study therapy. METHODS The occ...

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ژورنال

عنوان ژورنال: Arthritis Care & Research

سال: 2016

ISSN: 2151-464X

DOI: 10.1002/acr.22686